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Title
of the Collaborating Centre
:
WHO Collaborating Centre for Traditional
Medicine
Institution name : East-West Medical Research
Institute, Kyung Hee University
Exact name of the department which acts as
the WHO Collaborating Centre
:
8 Divisions of Institute
City and country of location : Seoul, Korea |
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1.
Implementation of the work plan for each main activity
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1-1. Work performed in relation to the terms
of reference |
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1.1.1. KRF (Korea Research Foundation) Research
Project |
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The Institute received funds from the Korea
Research Foundation in October 2001 as a new government
research project, which is a 6-year program. The grant
consisted of $150,000 from government and $75,000 from
Kyung Hee University in 2003. The title of this project
is ‘The Study of East-West Integrated Medicine on Pain
control’, and the principle investigator of this project
was professor Jin-Woo Kim, former head of this institute.
This project is composed of two teams as follows; |
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| (1) |
tThe 1st team |
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Title : Developments of Therapeutic Models on
East-West Integrated Medicine
Primary investigator : Yun-Ho Lee, OMD.
Department
of Acupuncture & Moxibustion,
College
of Oriental Medicine, Kyung Hee University
This team aims at development the therapeutic models
for arthritis by the East-West Integrated Medicine
at the East-West Arthritis Center, and to develop
a pain control model by East-West Integrated Medicine
at the East-West Pain Clinic.
We carried out ① a clinical study of the effectiveness
of East-West pain treatment on central poststroke
(CPSP) at the East-West pain clinic in our hospital.
We were able to evaluate its effect on alleviation
of pain and rehabilitation of CPSP patients who
were treated with electroacupuncture and Western
pain treatment for four weeks. This study was a
double-blind and randomized controlled trial. Seventy
patients diagnosed by their pain characteristics
of central pain from stroke were treated with sypathetic
nerve block, gabapentin, amitripyline, or electroacupuncture
for four weeks. Pain intensity through the visual
analogue scale (VAS), and improvements of mobility
and rehabilitation through the modified Barthel
index (MBI) and Rankin scale (RS), respectively,
before and after pain treatment were also assessed.
Bee venom therapy has been used for the treatment
of rheumatoid arthritis in traditional oriental
medicine. In addition to the clinical trial of bee
venom for therapeutic models of rheumatoid arthritis
at the East-West Arthritis Center for 2002, ② we
kept this clinical study. A double-blind and randomized
controlled trial was also performed to evaluate
the efficacy of the bee venom treatment with control
of Methotrexate for three months.
This work was supported by grant KRF-2001-005-F00025
from Center of Research Institute Program in the
Korea Research Foundation |
| (2) |
The 2nd team |
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Title : Development of Pain-control Method on
East-West Integrated Medicine
Primary investigator : Sabina Lim, OMD.
Department
of Meridian and Acupoint,
College
of Oriental Medicine, Kyung Hee University
This team intends to find new herbal medicine including
herbal prescription and herbal acupuncture for the
treatment of arthritis and neuropathic pain, and
to develop an ultrasonic therapeutic system on non-invasive
meridian points.
In addition to the project of the first year
(from October 2001 to September 2002), we kept
the study of screening of herbal medicine to develop
therapeutic agents for rheumatoid arthritis (RA)
in vitro and in vivo, and tried to make a new
herbal prescription for arthritis and pain control.
RA is an auto-immune disorder of unknown etiology
that is characterized by progressive joint destruction,
deformity, disability and premature death in most
patients. In results, several herbal medicine
showed acute anti-inflammatory and anti-nociceptive
effects on carrageenan induced paw edema. Among
them, KHM-10, exhibited chronic anti-inflammatory
and anti-nociceptive effects on complete Freund's
adjuvant-induced arthritis in rats through paw
edema, mechanical hyperalgesia, thermal hyperalgesia,
ankle flexion test. These herbal medicine may
be a promising therapy for the long-term treatment
of rheumatoid arthritis. Bee venom inhibited cell
proliferation and COX-2 espression at dendate
gyrus in rats on the acetic acid-induced hyperalgesia.
On the other hand, Ultrasonic therapeutic system
was developed and validated on non-invasive meridian
points.
This work was supported by grant KRF-2001-005-F00024
from Center of Research Institute Program of the
Korea Research Foundation. The above research
project can be summarized as follows.
Implementation of Activity :
- Effects of simultaneous Eastern and Western
treatment on pain (of osteoarthritic patients)
- Effects of simultaneous Eastern and Western
treatment on immunity (of patients with rheumatic
arthritis)
- Development of intensive care programs for arthritic
inpatients
- Development of a codiagnosis system model between
Eastern and Western medicine for pain in the East-West
pain clinic (of patients with central pain)
- Development of Eastern medication for arthritis
- Development of uninvasive ultrasonic Meridian
treatment system
Publications and Other Outcomes : Some parts
of outcomes were published and the rests of them
are in processing.
Evaluation : We played an even more important
role in promoting cooperation and collaboration
between Eastern and Western medicine than the
years before 2000. We plan to develop a workable
unified medical system based on these continuous
results.
Difficulties : There are two kinds of medicine
in Korea. One is Western medicine and the other
is Eastern medicine. Each medicine is rapidly
progressing separately in technology. Policies
that will promote more cooperation and collaboration
between the two medicines are required.
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1.1.2. KOSEF (Korea Science and Engineering
Foundation) Research Project |
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The institute carried out three research
project from the Korea Science and Engineering for 2003.
The contents and results of each of these projects were
as follows. The first project during the three years,
(1), was terminated because of the end of the project
duration. The 2nd project, (2), was carried out for the
first year of the project period. The 3rd project, (3),
was carried out only for the first year of the study period
and terminated because of resignation of the PI. The funds
for these projects were $50,000, $34,000 and $34,000,
respectively, for one year.
| (1) |
Title : Effects of acupuncture on alterations
of immune responses evoked by hypothalamus lesions
Primary investigator : Byung-Il Min, MD.
Department
of Physiology, College of Medicine,
Kyung
Hee University |
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Purpose of Research : A series of reports have
demonstrated that the occurrence of stress-associated
diseases has consistently increased in recent reduction.
It also reported that the stress has a close relationship
with the decrement of immune responses to foreign
antigens. There is no doubt that the neuronal system
and the immune system do not exist separately, rather
cooperate each other to sustain the homeostasis
of human body. Recently several reports strongly
suggested that the acupuncture therapy induces the
analgesia through the neuronal pathway and also
modulates the immune responses. The reduced immune
responses by stress are believed to be a result
of cooperative interactions between the hypothalamus,
pituitary grand and adrenal grand (H-P-A axis).
Especially the hypothalamus is the key element to
connect the neuronal sytem with the immune system.
In addition, it has been demonstrated that the selective
destruction of the nucleus in the hypothalamus induces
turbulence in immune and endocrine homeostasis.
The acupuncture stimuli not only covey the signal
to the hypothalamus and induce the analgesic effects,
but also increase the cytotoxic effect of natural
killer cells (NK cell) and influence of the balance
between CD4/CD8 T lymphocytes. However, there is
virtually no information available demonstrating
the direct connection between the acupuncture therapy
and the neuro-immune system. Therefore, this study
focuses on evaluating the acupuncture effects on
the immune system using an animal model with selective
destruction of hypothalamic nucleus in rat. Furthermore
this study can provide valuable information about
the mechanisms of acupuncture therapy on the immune
modulation.
Objectives of investigation during three consecutive
years: 1) 1st year - To evaluate immune responses
induced by electrocuting hypothalamic nuclei. 2)
2nd year - To investigate the acupuncture effects
on the immune responses induced by hypothalamic
lesions. 3) 3rd year - To elucidate mechanism involved
in the acupuncture effects on the immune responses
induced by hypothalamic lesions.
Contents of Research : 1) The evaluation of acupuncture
effects on immune responses induced by lateral hypothalamic
area (LHA) lesions - the measurement of NK cell
activity, cytokines, while giving acupuncture. 2)
The evaluation of acupuncture effects on immune
responses induced by anterior nucleus lesions -
the measurement of NK cell activity. 3) The evaluation
of acupuncture effects on immune responses induced
by medial preoptic area (MPO) lesions - the measurement
of NK cell activity as the above. 4) The evaluation
of acupuncture effects on analgesia induced by LHA,
MPO lesions using tail flick test. 5) The research
for the gene expression in hypothalamus after acupuncture
stimulation - microarray, real time PCR. 6) The
research of gene expression in spleen after acupuncture
stimulation - microarray, real time PCR, the measurement
of SOD proteins. 7) The evaluation of physiological
effects on immune responses when applied moxibustion
- the measurement of NK cell activity, T, B cell
proliferation, and cytokines - the evaluation of
activity of sympathetic nerve system (SNS) in immune
responses induced by moxibustion
Effectiveness of Research : We have found that:
1) LHA has been involved in the modulation of NK
cell activity induced by acupuncture. 2) Anterior
hypothalamus is involoved in the modulation of NK
cell activity, and also acupuncture boosted NK cell
activity. 3) MPO has not been involoved in the modulation
of NK cell activity induced by acupuncture. 4) LHA,
MPO lesions were not related to anlagesia using
tail flick test. 5) The microarray and PCR results
of hypothalamus show that EA treatment up-regulates
expression of genes associated with ① nerve growth
such as NGF induced factor A and VGF, ② signal transduction
such as 5HT3 receptor subunit, AMPA receptor binding
protein and Na-dependent neurotransmitter transporter,
and ③ anti-oxidation such as superoxide dismutase
and glutathione S-transferase. In addition, the
activity of the anti-oxidative enzyme, SOD of hypothalamus,
liver and RBC was enhanced compared to that of control.
6) The microarray and PCR results of the spleen
show that EA treatment up-regulates expression of
CD94, protein-tyrosine kinase and VCAM-1 mRNA, and
down-regulates expression of protein tyrosine phosphatase
and SHP-1 mRNA 7) Moxibustion affected the alteration
of NK cell activity, and along with INF-gamma, SNS
is suggested to be involved in these effects.
This work is supported by grant No. R01-2000-000-00170-0
from the Basic Research Program of the Korea Science
and Engineering Foundation. |
| (2) |
Title : The study of the genetic polymorphism
associated with rheumatoid arthritis by Sasang constitution
Primary investigator : Su-Young Kim, PhD.
East-West
Medical Research Institute
Kyung
Hee University |
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Backgrounds : Disease susceptibility of individuals
is expected to be different depending on their
personality traits. The Sasang Typology, a traditional
Korean medical typology, is known to explain the
individual differences of vulnerability to pathology
and proposed guidelines for the safe and effective
use of medical herbs depending on individual traits.
Objective : The purpose of this study is to examine
the susceptibility of the patients diagnosed by
rheumatoid arthritis to Sasang Typology.
Methods : This study is planned to detect the
susceptibility of the patients diagnosed with
rheumatoid arthritis to Sasang Typology. In order
to analyze the susceptibility of rheumatoid arthritis
to Sasang Typology, 147 rheumatoid arthritis patients
and 147 matched controls are assessed with QSCCII
question for Sasang Typology. Then the frequencies
of patients by Sasang constitution are compared
to those of control, which are statistically analyzed
and adjusted by age, sex, smoking status, alchol
intake, BMI, and economic status.
Results : The demographic characteristics of the
study population are similar in sex and age distribution,
smoking status, and alcohol intake (p>0.05).
147 rheumatoid arthritis patients and 147 matched
controls are assessed with QSCCII question for
Sasang constitution. Soeumin is the most susceptible
to rheumatoid arthritis compared to Taeumin or
Soyangin (Crude OR[95% CI]; 3.82[2.19-6.64]).
It is statistically significant after adjusting
age, sex, smoking status, alcohol intake, BMI,
and economic status (Adjusted OR[95% CI]; 3.01[1.47-6.15]).
Conclusion : It is suggested that the specific
Sasang Typology associated with rheumatoid arthritis
is used as its susceptibility marker and further
as basic data to prevent the risk factors for
rheumatoid arthritis.
This work is supported by grant No. R03-2002-000-00033-0
from the Basic Research Program of the Korea Science
and Engineering Foundation.
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Title : The absorption and metabolic pathways
of antimalarial drugs with stereoselectivity
Primary investigator : Kyoung-Ah Kim, PhD.
East-West
Medical Research Institute
Kyung
Hee University |
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Objectives : We first isolated human liver microsomes
from the human liver by a differential centrifugation
and stored them at -80 C. After this, we developed
a new method for detection of desethylchloroquine
and didesethylchloroquine, metabolites of chloroqine
and carboxyprimaquine, a metabolite of primaquine
using high-performance liquid chromatography (HPLC).
Human liver microsomes were incubated with various
concentrations of chloroquine or primaquine in the
mixture of NADPH-generating system for 30 min at
37 C. We draw Michaelis-Menten curve with these
results and calculated Km and Vmax values for metabolism
of chloroquine. Each CYP-isoform specific inhibitors
were co-incubated with chloroquine to determine
the CYP isoforms involved in its metabolism. Additionally,
chloroquine was also incubated with each various
cDNA-expressed CYP isoforms (CYP1A2, 2A6, 2B6, 2C8,
2C9, 2C19, 2D6, 2E1, 3A4, 3A5) to confirm the CYP
isoforms involved and calculated each Km and Vmax
value in each CYP. Finally, we did a correlation
study between chloroquine metabolism and metabolism
of CYP isoform-specific probe drugs with various
human liver microsomes to elucidate the metabolic
pathways of chloroquine. This method was also done
in primaquine study.
Brief Description of Research : We identified desethylchloroquine
as a main metabolite of chloroqine in human liver
microsomes but could not detect didesethylchloroquine.
Eadie-Hofstee plot of chlroquine metabolism showed
biphasic curve, suggesting the involvement of more
than two CYP isoforms in the metabolism of chloroquine.
From the experiments using cDNA-expressed CYP isoforms
and CYP isoform-specific inhibitors, we identified
CYP1A2, CYP2C8, CYP2D6, and CYP3A4/5 played crucial
roles in the metabolism of chloroquine. However,
we found chloroquine metabolism was correlated with
metabolism of CYP2C8 and CYP3A4/5, suggesting these
CYP isoforms are main metabolic enzymes of chloroquine.
We also identified CYP2C8 and CYP3A4/5 had crucial
role in the metabolism of primaquine in human liver
microsomes. We also isolated chiral forms of chloroquine
and primaquine to study stereoselective metabolism.
We submitted and published these result in Archives
of Pharmacal Research (vol 26, No 8, pp631-637,
2003)
This work is supported by grant No. R03-2002-000-00028-0
from the Basic Research Program of the Korea Science
and Engineering Foundation. |
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1.1.3. Vision 2000 Project - Kyung Hee University,
Pain and Neuroscience Team |
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Principle investigator of the Vision 2000
Project was Prof. Jin-Woo Kim, former head of this institute.
It was initiated in July 2000, admitted, supported and
proceeded by the Kyung Hee University task force team.
It was also terminated in 30 September 2003. All research
was carried out through cooperation between western medicine,
oriental medicine and pharmacy. The research team received
funds from university of $167,000 in 2003.
Title : Studies of therapeutic modalities and new
drugs on the east-west medicine
Primary Investigator : Sabina Lim, OMD.
Department
of Meridian and Acupoint,
College
of Oriental Medicine, Kyung Hee University
In order to study the therapeutic modalities and new
drugs on the East-West medicine, the research teams
investigated ① the effects of herbal medicines screened
in vitro to find the potential therapeutics for the
treatment of arthritis and pain. A lot of herbal medicine
showed inhibitory effects of PGE2 production, COX-2
and iNOS expression, and NO production on Raw 264.7
cells. ② The study was performed to develop oral therapeutics
for the treatment of arthritis and pain. In this aim,
several herbal medicines were also selected as effective
candidates, KHM-02 markedly inhibited inflammatory and
nociceptive effects on carrageenan induced paw edema
in Rats and on adjuvant-induced chronic arthritis. ③
Therapeutic modalities for arthritis and pain using
herbal acupuncture were developed. ④ Development of
the patch was conducted for the treatment of arthritis
and pain. The ant anti-inflammatory effects of herbal
medicine were tested in vitro and in vivo for patch
or cream. In other words, lots of herbal medicine exhibited
enzyme activities on hyaluronidase and trypsin in vitro,
and acetic acid-induced hyperalgesia in vivo. ⑤ The
toxicity test was performed for the herbal medicines
screened in vitro or in vivo to find the potential therapeutics
for the treatment of arthritis and pain.
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1.1.4. Development of Korean standard bronze
figures |
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Implementation of Activity : 10 professors
of the 11 colleges of Eastern medicine worked in cohesion
to develop the bronze figures
Publications and Other Outcomes : In processing
Evaluation : The development of the standard bronze figures
will allow for a more standardized training in universities
and training institutions of Korean Medicine. This development
is also regarded as having upgraded the quality of education
and raised esteem of Eastern medicine to the general public.
Difficulties : The price for each unit is yet high, due
to the difference in material. The former bronze figures
were usually made of plastic, but the new model is made
of copper. |
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1.1.5. Provision of training and special
lectures |
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Implementation of Activity : Invitational
lectures from global scholars
| Name |
Date |
Organization |
Subject |
| Peter Hand |
2000.05.06 |
Univ. of Pennsylvania |
Development neuronal plasticity |
| Gregory Y Golden |
2000.05.25 |
Univ. of Thomas Jefferson |
Alzheimers disease |
| Margaret Naeser |
2000.05.25 |
Univ. of Boston |
Acupuncture and laser |
| Keum Hwa Kim Choi |
2000.09.19 |
Univ. of Minnesota |
Invitational seminar |
| Jung Soo Han |
2001.03.30 |
Johns Hopkins Univ. |
Invitational seminar |
| Kwang-soo Kim |
2001.04.09 |
Harvard Univ. Med school |
Invitational seminar
Exchange of information
Agreement on long-term training for graduates |
| Vladimir Vuksan |
2002.10.30 |
Univ. of Toronto |
Effects of red ginseng on patients with
diabetes |
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Publications and Other Outcomes : None
Evaluation : The invitation of those scholars facilitated
informational exchanges between many nations. It also
gave Korean Eastern medical practitioners and education
personnel chances to obtain information which will be
valuable in both training future medical manpower and
directly treating patients.
Difficulties : Due to the schedules of the scholars, not
many visited our center in the period between December
to April. |
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1.2. Further Activity |
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1.2.1. Formulating policies on the protection
and conservation of indigenous health resources in Korea |
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(1) Establishment of the Korean Medicine
Promotion Act in Korea (2003)
(2) Procurement of additional Eastern public health doctors
(2003) |
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1.2.2. Fostering respect for the cultural
integrity of traditional medicine |
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(1) Relating tourism to Eastern medicine
- travel packages including Eastern Medical hospitals
have been developed
- 3 major TV series have been broadcasted; some of which
are attracting many tourists
(2) A private Korean Medical doctor for the president
has been appointed.
(3) Sports-related activities
- providing medical support for the Olympics and World
Cup games |
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1.2.3. Public Relations activities |
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Implementation of Activity :
- Media briefings through various broadcasting channels
including MBC, SBS, and Arirang TV
- Publications in various magazines
- Internet exposure of the 11 Eastern medical colleges
and other organizations
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| Web page
address list |
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Kyung
Hee University
Kyung Hee Medical Center
Institute of Oriental Medicine at Kyung Hee Univ.
Kyung Hee College of Oriental Medicine
Kyung Won University
Daegu Haany University
Daejeon University
Dongguk University
Dongshin University
Dong-Eui University
Sangji University
Semyung University
Woosuk University
Wonkwang University
East-West Medical Research Institute
Graduate School of East-West Medical Science
The Association of Korean Oriental Medicine
Korean Acupuncture and Moxibustion
The Korean Society of Meridian and Acupoint
The Korean Institute of Herbal Acupuncture |
http://www.khu.ac.kr/
http://www.khmc.or.kr/
http://www.iomkhu.com/
http://omc.khu.ac.kr/
http://www.kyungwon.ac.kr/
http://www.dhu.ac.kr/
http://www.dju.ac.kr/
http://wwwk.dongguk.ac.kr/
http://www.dongshinu.ac.kr/
http://www.deu.ac.kr
http://www.sangji.ac.kr/
http://www.semyung.ac.kr/
http://www.woosuk.ac.kr/
http://come.wonkwang.ac.kr/
http://www.kewmri.re.kr/
http://web.kyunghee.ac.kr/~gsm/
http://www.koma.or.kr/
http://www.acumoxa.or.kr/
http://www.acupoint.org/
http://www.kiha.co.kr/ |
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Publications and Other Outcomes :
- 3 major TV series featuring Eastern Medicine from 2
major broadcasting stations
- a 26-piece documentary featuring Eastern Medicine named
Healthfinder from Arirang TV
- numerous fixed corners on health and Eastern Medicine
- many online and offline magazines on Eastern Medicine
Evaluation : Our public relations efforts, combined with
other efforts in a similar direction, have led to a big
increase in exposure to media, especially television broadcasting.
Many special documentaries and features have been filmed,
and 3 major TV series dealing with Eastern medicine have
been aired within the 4-year period. One is currently
on air, and our efforts combined with such results have
led to a major elevation in the public's regard for Eastern
medicine, and has formed a national background which has
been invaluable in the formation of some major policies
within this time period.
Difficulties : Before the results of our efforts were
presented to the general public, there was considerably
less enthusiasm for Eastern Medicine, and the general
public did not respond well at first to the infrequent
exposure. But after the major results came to the public,
the responses became very gratifying. |
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1.2.4. Revision of the terms of reference |
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We wish to revise the terms of reference
for the period 2004-2008, if possible, as described below
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(1) To cooperate with the WHO in studying the best
ways of harmonizing the existing dual medical system
- Eastern and Western medicine - with a view to developing
a workable unified medical care system
(2) To encourage and strengthen research into evidence-based
practice of traditional medicine
(3) To establish appropriate standards of traditional
medicine
(4) To develop a national policy for traditional medicine
(5) To promote public awareness of and access to traditional
medicine
(6) To foster respect for the cultural integrity of
traditional medicine
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1.2.5. Preparation of the terms of reference
of the next designation period (4 years) |
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| (1) |
To cooperate with the WHO in studying the best
ways of harmonizing the existing dual medical system
- Eastern and Western medicine - with a view to
developing a workable unified medical care system
- International symposium on East-West medicine
by School of Oriental Medicine, Graduate school
of East-West Medical Science, Institute of Oriental
Medicine and related organization |
| (2) |
To encourage and strengthen research into evidence-based
practice of traditional medicine
- Announcement of excellent paper on East-West medicine
- Inspection of Ko-Hwang Medical Award |
| (3) |
To establish appropriate standards of traditional
medicine
- Union and cooperation of the 11 Eastern medical
colleges and other organizations |
| (4) |
To develop a national policy for traditional medicine
- Establishment of the Korean Medicine Promotion
Act in Korea (2003)
- Media briefings |
| (5) |
To promote public awareness of and access to traditional
medicine
- Update the Korean homepage on the Web site and
create an English homepage |
| (6) |
To foster respect for the cultural integrity of
traditional medicine
- travel packages including Eastern Medical hospitals
have been developed
- 3 major TV series have been broadcasted; some
of which are attracting many tourists |
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1.3. Research papers published in 2003 |
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| (1) |
Mi-Hyeon Jang, Sabina Lim, Seung-Moo Han, Hi-Joon
Park, Insop Shin, Jin-Woo Kim, Nam-Jae Kim, Ji-Suk
Lee, Kyung-Ah Kim, Chang-Ju Kim
Harpagophytum Procumbens Suppresses Lipopolysaccharide-Stimulated
Expressions of Cyclooxygenase-2 and Inducible Nitric
Oxide Synthase in Fibroblast Cell Line L929
J Pharmacol Sci 93, 367-371 (2003) |
| (2) |
Kwang Sik Suh, Gwanpyo Koh, Cheol Young Park,
Jeong Taek Woo, Sung Woon Kim, Jin Woo Kim, In Kook
Park, Young Seol Kim
Soybean isoflavones inhibit tumor necrosis factor-α-induced
apoptosis and the production of interleukin-6 and
prostaglandin E2 in osteoblastic cells
Phytochemistry 63 (2003) 209-215 |
| (3) |
Kwang Sik SUH, Yeon Ho NAN, Young Min AHN, Nam
Jae KIM, Cheol Young PARK, Gwanpyo KOH, SeungJoon
OH, Jeong Taek WOO, Sung Woon KIM, Jin Woo KIM,
Young Seol KIM
Effect of Scutellariae Radix Extract on the High
Glucose-Induced Apoptosis in Cultured Vascular Endothelial
Cells
Biol. Pharm. Bull. 26(11) 1629-1632 (2003) |
| (4) |
Jung-Ae HONG, Seok-Hee CHUNG, Jong-Soo LEE, Sung-Soo
KIM, Hyung -Dae SHIN, Hong KIM, Mi-Hyeon JANG, Taeck-Hyun
LEE, Baek-Vin LIM, Young-Pyo KIM, Chang-Ju KIM
Effects of Paeonia radix on 5-Hydroxytryptamine
Synthesis and Tryptophan Hydroxylase Expression
in the Dorsal Raphe of Exercised Rats
Biol. Pharm. Bull. 26(2) 166-169 (2003) |
| (5) |
Mi-Hyeon Jang, Min-Chul Shin, Gyo-Sung Koo, Choong-Yeol
Lee, Ee-Hwa Kim, Chang-Ju Kim
Acupuncture decreases nitric oxide synthase expression
in periaqueductal gray area of rats with streptozotocin-induced
diabetes
Neuroscience Letters 337 (2003) 155-158 |
| (6) |
Min-Hyeon Jang, Mi-Chul Shin, Sabina Lim, Seung-Moo
Han, Hi-Joon Park, Insop Shin, Ji-Suk Lee, Kyoung-Ah
Kim, Ee-Hwa Kim, Chang-Ju Kim
Bee Venom Induces Apoptosis and Inhibits Expression
of Cyclooxygenase -2 mRNA in Human Lung Cancer Cell
Line NCI-H1299
J Pharmacol Sci 91, 95-104 (2003) |
| (7) |
Mi-Hyeon Jang, Hyun-Kyung Chang, Min-Chul Shin,
Taeck-Hyun Lee, Young-Pyo Kim, Ee-Hwa Kim, Chang-Ju
Kim
Effect of Ginseng radix on c-Fos Expression in the
Hippocampus of Streptozotocin-Induced Diabetic Rats
J Pharmacol Sci 91, 149-152 (2003) |
| (8) |
Hong KIM, Mi-Hyeon JANG, Min-Chul SHIN, Hyun-Kyung
CHANG, Taeck-Hyun LEE, Baek-Vin LIM, Chang-Young
JUNG, Choong-Yeol LEE, Ee-Hwa KIM, Chang-Ju KIM
Folium mori Increases Cell Proliferation and Neuropeptide
Y Expression in Dentate Gyrus of Streptozotocin-Induced
Diabetic Rats
Biol. Pharm. Bull. 26 |
| (9) |
Mi-Hyeon Jang, Min-Chul Shin, Baek-Vin Lim, Hyun-Bae
Kim, Young-Pyo Kim, Ee-Hwa Kim, Hong Kim, Mal-Soon
Shin, Sung-Soo Kim, Chang-Ju Kim
Acupuncture Increases Nitric Oxide Synthase Expression
in Hippocampus of Streptozotocin-induced Diabetic
Rats
The American J Chinese Medicine 31(2) 305-313 (2003) |
| (10) |
Mi-Hyeon Jang, Min-Chul Shin, Youn-Jung Kim, Chang-Ju
Kim, Joo-Ho Chung
Protective Effect of Acanthopanax senticosus Against
Ethanol-induced Apoptosis of Human Neuroblastoma
Cell Line SK-N-MC
The American J Chinese Medicine 31(3) 379-388 (2003) |
| (11) |
Mi-Hyeon Jang, Min-Chul Shin, Taeck-Hyun Lee,
Baek-Vin Lim, Mal-Soon Shin, Byung-Il Min, Hong
Kim, Sonhae Cho, Ee-Hwa kim, Chang-Ju Kim
Acupuncture suppresses ischemia-induced increase
in c-Fos expression and apoptosis in the hippocampal
CA1 region in gerbils
Neuroscience Letters 347 (2003) 5-8 |
| (12) |
Ji-Eun Kang, Hye-Jung Lee, Sabina Lim, Ee-Hwa
Kim, Tae-Hee Lee, Mi-Hyeon Jang, Min-Chul Shin,
Baek-Vin Lim, Youn-Jung Kim, Chang-Ju Kim
Acupuncture Modulates Expressions of Nitric Oxide
Synthases and c-Fos in Hippocampus After Transient
Global Ischemia in Gerbils
The American J Chinese Medicine 31(4) 581-590 (2003) |
| (13) |
Yeong-Ki Min, Seok-Hee Chung, Jong-Soo Lee, Sung-Soo
Kim, Hyun-Dae Shin, Baek-Vin Lim, Min-chul Shin,
Mi-Hyeon Jang, Ee-Hwa Kim, Chang-Ju Kim
Red Ginseng Inhibits Exercise-Induced Increase in
5-Hydroxytryptamine Synthesis and Tryptophan Hydroxylase
Expression in Dorsal Raphe of Rats
J Pharmacol Sci 93, 218-221 (2003) |
| (14) |
Min-Chul Shin, Mi-Hyeon Jang, Hyun-Kyung Chang,
Sabina Lim, Seung-Moo Han, Hi-Joon Park, Insop Shim,
Ji-Suk Lee, Kyung-Ah Kim, Chang-Ju Kim
Modulation of Chelidonii herba on glycine-activated
and glutamate -activated ion currents in rat periaqueductal
gray neurons
Clinica Chimica Acta 337 (2003) 93-101 |
| (15) |
Mi-Hyeon JANG, Min-Chul SHIN, Taeck-Hyun LEE,
Geon-Ho BAHN, Hye-Sook SHIN, Sabina LIM, Ee-Hwa
KIM, Chang-Ju KIM
Effect of Puerariae radix on c-Fos Expression in
Hippocampus of Alcohol -Intoxicated Juvenile Rats
Biol. Pharm. Bull. 26(1) 37-40 (2003) |
| (16) |
Ee-Hwa KIM, Mi-Hyeon JANG, Min-Chul SHIN, Mal-Soon
SHIN, Chung-Ju KIM
Protective Effect of Aqueous Extract of Ginseng
radix against 1-Methyl-4 -phenylpyridinium-Induced
Apoptosis in PC12 Cells
Biol. Pharm. Bull. 26(12) 1668-1673 (2003) |
| (17) |
Jong-Ju Lee, Eu-Teum Hahm, Byung-Il Min, Seung-Ho
Han, Jung-Je Cho, Young-Wuk Cho
Roles of protein kinase A and C in the opioid potentiation
of the GABAA response in rat periaqueductal gray
neuron
Neuropharmacology 44 (2003) 573-583 |
| (18) |
Jae-Bok Han, Sang-Duck Oh, Ki-Seok Lee, Ki-Soon
Choi, Young-Wuk Cho, Hyun-Jong Ahn, HyunSu Bae,
Byung-Il Min
The role of the sympathetic nervous system in moxibustion-induced
immunomodulation in rats
Journal of Neuroimmunology 140 (2003) 159-1624)
434-437 (2003) |
| (19) |
Gi-Seog Lee, Jae-Bok Han, Min-Kyu Shin, Moo-Chang
Hong, Sung-Woon Kim, Byung-Il Min, HyunSu Bae
Enhancement of electroacupuncture-induced analgesic
effect in cholecystokinin-A receptor deficient rats
Brain Research Bulletin 62 (2003) 161-164 |
| (20) |
Eui-joon Lee, Eunjung Ko, Jinwoo Lee, Samwoong
Rho, Seonggyu Ko, Min-Kyu Shin, Byung-il Min, Moo-Chang
Hong, Si-young Kim, Hyunsu Bae
Ginsenoside Rg1 enhances CD4+ T-cell activities
and modulates Th1/Th2 differentiation
International Immunopharmacology (2003), in press |
| (21) |
Sabina Lim, Yeun-Hee Ryu, Seung-Tae Kim, Mee-Suk
Hong, Hi-Joon Park
Acupuncture increases neuropeptide Y expression
in hippocampus of maternally-separated rats
Neuroscience Letters 343 (2003) 49-52 |
| (22) |
Hi-Joon Park, Sabina Lim, Wan-Seok Joo, Chang-Shik
Yin, Hyang-Sook Lee, Hye-Jung Lee, Jung-Chul Seo,
Kanghyun Leem, Yang-Sun Son, Youn-Jung Kim, Chang-Ju
Kim, Yong-Sik Kim, Joo-Ho Chung
Acupuncture prevents 6-hydroxydopamine-induced neuronal
death in the nigrostriatal dopaminergic system in
the rat Parkinson's disease model
Experimental Neurology 180 (2003) 92-97 |
| (23) |
Ji Hoon Kim, Byung-Il Min, Heung Sik Na, Dong
Suk Park
Relieving effects of electroacupuncture on mechanical
allodynia in neuropathic pain model of inferior
caudal trunk injury in rat: mediation by spinal
opioid receptors
Brain Research 998 (2004) 230-236 |
| (24) |
Byung-Shik Cheong, Sang-Soo Nam, Do-Young Choi
Modulation of Corydalis tuber on Glycine-induced
Ion Current in Acutely Dissociated Rat Periaqueductal
Gray Neuron
Korean J Oriental Medicine 24(4) 34-42 (2003) |
| (25) |
Young-Chul Kim, Jang-Hoon Lee, Hong-Jung Woo
Effect of Samul-tang (Siwu-tang) on Procollagen
Synthesis in Cultured Murine Hepatic Non-parenchymal
Cells
Korean J Oriental Medicine 24(4) 120-126 (2003) |
| (26) |
Do Young Choi, Doo Ik Lee, Su Young Kim, Keon
Sik Kim, Jae Dong Lee, Yun Ho Lee
Specific Electric Acupuncture for the Management
of the Central Poststroke Pain
The Korean Pain Research Society 13, 74-80 (2003) |
| (27) |
Keon Sik Kim, Su Young Kim, Doo Ik Lee, Do Young
Choi, Jae Dong Lee, Yun Hoo Lee
Thermographic Findings in Central Poststroke Pain
- Correlation between the changes of pain and temperature
-
J Korean Society of Diagnostic Thermology 3(1) 34-39
(2003) |
| (28) |
Lee Hyun-jong, Kim Su-young, Lee Sang-Hoon, seo
Dong-mino, Lee Doo-ik, Kim Keun-sik, Lee Jae-dong,
Lee Yun-ho, Yang Hyung-in, Park Jae-kyung, Choi
Do-young
Effect of East-West pain treatment for Central Poststroke
Pain on alleviation of pain and Rehabilitation
J Kor. Acupuncture & Moxibustion Society 20(2)
42-49 (2003) |
| (29) |
Lee Sang-hoon, Lee Hyun-jong, Park Sang-Min, Kim
Su-young, Park Jae-kung, Hong Seung-jae, Yang Hyung-in,
Lee Jae-dong, Choi Do-young, Kim Keon-Sik, Lee Doo-ik,
Lee Yun-ho
Effects of Bee Venom Acupuncture on the Rahabilitation
and Quality of Life in Rheumatoid Arthritis Patients
J Korean Institute of Herbal Acupuncture 5(2) 63-70
(2003) |
| (30) |
Kim Kyoung-ah, Lee Ji-suk, Park Hi-joon Park,
Jin-Woo Kim, Chang-Ju Kim, In-Sop Shim, Seung-Moo
Han, Sabina Lim
The Inhibitory Effect of Achyranthes bidentata radix
Extracts on Cytochrome P450-Catalyzed Reactions
in Human Liver Microsomes
J Korean Oriental Med 2003; 24(2): 40-46 |
| (31) |
Lee Sang-hoon, Lee Hyun-jong, Baek Yong-hyeon,
Kim Su-young, Park Jae-kyung, Hong Seung-jae Hong,
Yang Hyung-in, Kim Keon-sik, Lee Jae-dong, Choi
Do-young, Lee Doo-ik, Lee Yun-ho
Effects of Bee Venom on the pain, edema, and acute
inflammatory reactant of Rheumatoid Arthritis patients
J Kor. Acupuncture & Moxibustion Society 20(2)
77-84 (2003) |
| (32) |
Park Hi-joon, Ryu Yeon-hee, Hong Mee-suk, Kim
Seung-tae, Lim Sabina
The effect of HT7 acupuncturing on the food intake
and hypothalamic neuropeptide Y expression changed
by maternal separation in rat pups
J Kor. Acupuncture & Moxibustion Society 20(4)
93-101 (2003) |
| (33) |
Lee Sang-hoon, Hong Seung-jae, Kim Su-young, Yang
Hyung-in, Lee Jae-dong, Choi Do-young, Lee Doo-ik
Lee, Lee Yun-Ho
Randomized Controlled Double Blind Study of Bee
Venom Therapy on Rheumatoid Arthritis
J Kor. Acupuncture & Moxibustion Society 20(6)
80-88 (2003) |
| (34) |
Hyun-Suk Seung, Young-Chul Kim, Jang-Hoon Lee,
Hong-Jung Woo
Inhibitory Effect of Injinchunggantang (Yinchenqinggan-tang)
on Hepatic Sclerosis
Korean J Orient. Int. Med. 2003: 24(1) 21-32 |
| (35) |
Dae-Won Yeo, Jin-Sung Kim, Sang-Hyub Yoon, Bong-Ha
Ryu, Ki-Won Ryu
Experimental Studies on Antitumor Effect and Immune
Responses of Bunsimgieum
Korean J. Orient. Int. Med. 2003: 24(2) 315-328 |
| (36) |
Sang-Hyub Yoon, Bong-Ha Ryu, Ki-Won Ryu, Jin-Sung
Kim
Evaluation for Therapeutic Effectiveness of Banwhasashim-tang
in Functional Dyspepsia
Korean J. Orent. Int. Med. 2003: 24(2) 329-336 |
| (37) |
Hyung-Kil Yang, Young-Suk Kim, Hyung-Sup Bae,
Ki-Ho Cho, Ji-Eun Shin, Nam-Jae Kim, Dong-Hyun Kim
Rhei Rhizoma and Chunghyuldan Inhibit Pancreatic
Lipase
Natural Product Sciences 9(1): 38-43 (2003) |
| (38) |
BAE, EUN-AH, NA-YOUNG KIM, MYUNG JOO HAN, MIN-KYUNG
CHOO
Transformation of Ginsenosides to Compound K (IH-901)
by Lactic Acid Bacteria of Human Intestine
J. Microbiol. Biotechnol. (2003), 13(1), 9-14 |
| (39) |
Hae-Woong Lee, Min-Kyung Choo, Eun-Ah Bae, Dong-Hyun
Kim
β-Glucuronidase inhibitor tectorigenin isolated
from the flower of Pueraria thunbergiana protects
carbon tetrachloride-induced liver injury
Liver International 2003, 23, 221-226 |
| (40) |
Min-Kyung Choo, Eun-Kyung Park, Myung-Joo Han,
Dong-Hyun Kim
Antiallergic Activity of Ginseng and its Ginsenosides
Planta Medica 2003; 69: 518-522 |
| (41) |
Yeo-Ok Han, Myung Joo Han, Sung-Hwan Park, Dong-Hyun
Kim
Protective Effects of Kakkalide From Flos Puerariae
on Ethanol-Induced Lethality and Hepatic Injury
Are Dependent on Its Biotransformation by Human
Intestinal Microflora
J Pharmacol Sci 93, 331-336 (2003) |
| (42) |
Eun-Kyung PARK, Min-Kyung CHOO, Eun-Jin KIM, Myung
Joo HAN, Dong-Hyun KIM
Antiallergic Activity of Ginsenoside Rh2
Biol. Pharm. Bull. 26(11) 1581-1584 (2003) |
| (43) |
Hyun-Ju Jung, Hee-Juhn Park, Ryung-Gue Kim, Kyoung-Min
Shin, Joohun Ha, Jong-Won choi, Hyoung Ja Kim, Young
Sup Lee, Kyung-Tae Lee
In vivo Anti-Inflammatory and Antinociceptive Effects
of Liriodendrin Isolated from the Stem Bark of Acanthopanax
senticosus
Planta Medica 2003; 69: 610-616 |
| (44) |
Hyeon Ka, Hee-Juhn Park, Hyun-Ju Jung, Jong-Won
Choi,Kyu-Seok Cho, Joohun Ha, Kyung-Tae Lee
Cinnamaldehyde induces apoptosis by ROS-mediated
mitochondrial permeability transition in human promyelocytic
leukemia HL-60 cells
Cancer Letters 196 (2003) 143-152 |
| (45) |
Rung-Gyu KIM, Kyung-Min SHIN, Young-Kwan KIM,
Hyeh-Jean JEONG, Joohun HA, Jong-Won CHOI, Hee-Juhn
PARK, Kyung-Tae LEE
Inhibition of Methanol Extract from the Aerial Parts
of Saururus chinensis on Lipopolysaccharide-Induced
Nitric Oxide and Prostagladin E2 Production from
Murine Macrophage RAW 264.7 Cells
Biol. Pharm. Bull. 26(4) 481-486 (2003) |
| (46) |
Hee-Juhn Park, Ryung-Gue Kim, Bo-Rim Seo, Joohun
Ha, Byung-Tae Ahn, Song-Hae Bok, Yong Sup Lee, Hyoung
Ja Kim, Kyung-Tae Lee
Saucernetin-7 and Saucernetin-8 Isolated from Saururus
chinensis inhibit the LPS-induced Production of
Nitric Oxide and Prostaglandin E2 in Macrophage
RAW 264.7 Cells
Planta Medica 2003; 69: 947-950 |
| (47) |
Shin Yong-Wuk, Kim Dong-Hyun, Kim Nam-Jae
Studies on the Processing of Crude Drugs(Ⅶ) - on
the Constituents and Biological Activities of Gardeniae
Fructus by Processing -
Kor. J. Pharmacogn. 34(1) 45-54 (2003) |
The full contents of Nos. 1-25 and 37-46 were written
in English. |
| |
|
| |
1.4. Publications in 2003 |
| |
|
| |
1.4.1. East-West Medical Research Institute
Journal 2002 : |
| |
This book contains 35 articles which were
researched and published in this institute. The journal
is attached. |
| |
|
| |
1.4.2. Alternative and Complementary Diabetes
Care : |
| |
The book Alternative and complementary Diabetes
Care by Diana W. Guthrie was translated into Korean by
Prof. Young-Seol Kim (MD) and Prof. Young-Min Ahn (OMD).
The book is attached. |
| |
|
| 2. Collaboration between the centre and
the WHO |
| |
|
| |
2.1. Visits by WHO staff (HQ and /or Regional
Office) to the centre |
| |
Name of WHO staff : Dr. George J. Slama
WHO country liaison officer, Republic of Korea
Dr. George J. Slama (WHO collaborating centre, WHO CC)
was met and welcomed by the vice president for Medical
Affairs and director general of the Medical Center of
the Kyung Hee University, Prof. Choong Yoon, and by the
director of the WHO CC, Prof. Kim Jin-Woo on 6 March 2003.
The WHO CLO introduced himself and thanked the Director
for the recently submitted 2002 annual report and 2003
work plan of the WHO Collaborating Centre. The points
of meeting were as follows :
| (1) |
The history of the East-West Medical Research
Institute and WHO CC, its cooperation with the WHO
and its current activities. |
| (2) |
Training programmes for traditional medicine professionals |
| (3) |
tSupplemental information on the international
activities of the WHO CC in addition to the information
provided in the 2002 annual report. |
|
| |
|
| |
2.2. Visits by centre staff to the WHO (HQ
and /or Regional Office) |
| |
- None. |
| |
|
| |
2.3. Use of the centre staff by WHO |
| |
We were requested to support and collaborate
the project on traditional medicine from the World Health
organization (WHO). These requests from WHO numbered seven
items during the period 2003. Some of them were already
answered and the rest of them are in process of response.
| (1) |
WHO draft guidelines on safety monitoring and
pharmacovigilance of herbal medicines : Request
for the development of a strategy to promote the
safety, efficacy and quality of traditional medicine
(Dr. Xiaorui Zhang, Coordinator, Traditional Medicine
(TRM), Department of Essential Drugs and Medicines
Policy (EDM))(from 18 February, 2003 to the end
of May, 2003). |
| (2) |
Linking Up Database on Traditional Medicine between
the World Health Organization and WHO collaborating
Centres for Traditional Medicine : Request to strengthen
the adopted Executive Board Resolution (document
reference number: EB111.R.12), which requests the
director-general of WHO to see, together with WHO
Collaborating Centres, evidence-based information
on quality, safety and cost -effectiveness of traditional
therapies so as to provide guidance to member states
on definition of products to be included in national
directives and proposals on traditional-medicine
policy as used in national health systems (Dr. Chen
Ken, Regional adviser, Traditional Medicine)(from
17 February, 2003 to 14 April, 2003). |
| (3) |
WHO Medicines Strategy 2004-2007 (Dr. Jonathan
D. Quick)(from 27 March, 2003 to 15 May, 2003) :
The WHO Medicine Strategy is intended to be a guide
for action for the WHO, but also policy makers,
managers, and other stakeholders in the area of
medicine. It will also be used as a communications
tool portraying our vision to key partners. As a
WHO collaborative centre in this field, the WHO
wants our institute to play a vital role in implementing
this shared agenda and responding effectively to
the needs of the people the WHO serves and to provide
points of view on revised draft to update the contents
of the WHO Medicines Strategy 2000-2003. The point
of views the WHO wants to get were as follows :
① Does the document present a clear picture of the
major challenges currently being faced, and the
way WHO is planning to respond to them in the next
four years?
② Are there any important omissions-areas in which
you feel WHO should be involved, but for which no
work is planned?
③ Are there any aspects that you feel should be
omitted-either because they are unimportant or because
you feel they should be undertaken by others? |
| (4) |
WHO monographs on selected medicinal plants, Volume
4 (by Dr Xiaorui Zhang, Coordinator, Traditional
Medicine (TRM), Department of Essential Drugs and
Medicines Policy (EDM), from 31 July, 2003 to the
end of November, 2003) : Request to help us to provide
the comments and additional scientific information
on eight draft manuscripts on the monographs with
the proposed list of medicinal plants and format
(Fructus Agni Casti, Cortex Berberidis, Gummi Boswellii,
Semen Cardamomi, Lichen Islandicus, Cortex Magnoliae,
Herba Millefolii, and Flos Trifolii) |
| (5) |
WHO guidelines on safety monitoring and pharmacovigilance
of Herbal Medicines : The 2nd comments on the firsts
draft of the draft Guidelines, especially, on the
suggestion to include an example of a reporting
form for adverse events related to herbal medicine
(By Dr. Xiaorui Zhang, Coordinator, Traditional
Medicine (TRM), Department of Essential Drugs and
Medicines Policy (EDM), from 21 October, 2003 to
15 December, 2003). |
| (6) |
Proposed WHO intermational standard terminology
in acupuncture for basic training : (By Dr. Xiaorui
Zhang, Coordinator, Traditional Medicine (TRM),
Department of Essential Drugs and medicnes policy
(EDM), from 1 October, 2003 to the end of February,
2004) : Invitation to join and support a new project
as part of the implementation of WHO traditional
Medicine Strategy : 2002-2005 in May 2002, one major
objectives of which is to promote rational use of
traditional medicine. |
| (7) |
WHO guidelines for assessing quality of herbal
medicines with reference to contaminants and residues
: (By Dr Xiaorui Zhang, Coordinator, traditional
Medicine (TRM), Department of Essential Drugs and
Medicines Policy (EDM), from 20 November, 2003 to
the end of January, 2004) : Support and collaboration
on the project carried out as a joint effort between
the traditional medicine (TRM) and the Food Safety
(FOS) programmes at the WHO Headquarters in Geneva. |
|
| |
2.4. Support provided by centre staff for
courses cosponsored or organized by the WHO (HQ and /or
Regional Office) |
| |
- None |
| |
|
| |
2.5. WHO financial support to the centre
through contractual or Technical Services Agreement |
| |
- None |
| |
|
| |
2.6. Other type of support provided by the
WHO |
| |
- None |
| |
|
| |
2.7. Any other collaborative activities |
| |
- None |
| |
|
| |
2.8. Any difficulties encountered in the
collaboration |
| |
| (1) |
Deficiency of recognition in the type of collaboration |
| (2) |
Continuous PR about WHO collaborating centers
from the WHO deployed personnel to our centre would
be appreciated |
|
| |
|
| |
2.9. Suggestions for increased and improved
collaboration with the WHO |
| |
| (1) |
We wish to play a leading role in holding international
conventions for the standardization of traditional
medicine. |
| (2) |
Early notice from WHO on cooperative activities,
at least 6 months in advance, would improve cooperation. |
|
| |
|
| 3. Collaboration with other WHO collaborating
centres |
| |
|
| |
3.1. Name(s) of the other WHO collaborating
centre(s) with which the centre has collaborated |
| |
| (1) |
Institute of Chinese Materia Medica, Chinese Academy
of Traditional Chinese Medicine, Beijing, People's
Republic of China (from 2001) |
| (2) |
Department of Japanese Oriental Medicine, Toyama
Medical and Pharmaceutical University, Toyama, Japan
(from 2001) |
|
| |
|
| |
3.2. Name of the network of collaborating
centres with which the centre belongs |
| |
- None |
| |
|
| |
3.3. Nature of the collaboration |
| |
| (1) |
Agreements concluded on international exchange
of education and research (from 2000) : Conclusion
of these exchange agreements with prominent foreign
institutions has made recognized the value of Korean
Medicine internationally and has helped in securing
a bridgehead for our clinical and educational programs
in advancing to the global society. |
| (2) |
Oriental medicine education program for international
care practitioners |
| (3) |
Advice activity of our researcher at WHO |
|
| |
|
| |
3.4. Outcome of the collaboration |
| |
| (1) |
Agreements concluded on international exchange
of education and research (from 2000)
- Institute of Chinese Materia Medica, Chinese Academy
of Traditional Chinese Medicine, Beijing, People's
Republic of China (2001.12.2) : exchange agreement
concluded for a herbal educational and research
facility
- Department of Japanese Oriental Medicine, Toyama
Medical and Pharmaceutical University, Toyama, Japan
(2001.6.22) : exchange agreement concluded for a
herbal educational and research facility |
| (2) |
Oriental medicine education program for international
care practitioners
(Kyung Hee University's postgraduate hospital residency
certification program)
- Becky A Boros, D.C., Dipl. Ac. from Chicago, Illinois |
| (3) |
Advice activity of our researcher at WHO
- Yong Suk Kim (researcher at Kyung Hee East-West
medical center and professor at Kyung Hee College
of Oriental Medicine)
: WHO/WPRO (Temporary adviser 2nd consultation meeting
on traditional and modern medicine) (2003.9.17-2003.9.20)
: WHO/WPRO (Temporary adviser Informal consultation
meeting on development of standard international
acupuncture of location) (2003.10.31-2003.11.1) |
|
| |
|
| |
3.5 Suggestions for increased and improved
collaboration with other WHO collaborating centers |
| |
: Further publicity on the role of our institute
in the standardization of traditional medicine would be
appreciated. |
| |
|
| |
|
| |
- END - |
|
|
|
|
